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2020 Vol.32, Issue 3 Preview Page

Research Article

Antioxidant Effects of Populus Tomentiglandulosa Extracts in Sprague-Dawley Rats

Sprague Dawley Rats을 이용한 현사시나무 추출물의 항산화 효능 평가

S. I. Choi1
,
O. H. Lee2
,
J. D. Kim2†
최 선일1
,
이 옥환2
,
김 종대2†
1Postgraduate Student, Department of Food Science and Biotechnology, Kangwon National University
2Professor, Department of Food Science and Biotechnology, Kangwon National University
1강원대학교 바이오산업공학부 식품생명공학전공 대학원생
2강원대학교 바이오산업공학부 식품생명공학전공 교수
*jongdai@kangwon.ac.kr
31 December 2020. pp. 353-359
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Abstract

This study aimed to investigate the antioxidant potential and free radical generation ability of Populus tomentiglandulosa (PT) extract in Sprague-Dawley (SD) rats. Male SD rats were fed a diet supplemented with 0.5% PT extract, as recommended by American Institute of Nutrition (AIN) for 4 weeks. Free radical generation and antioxidant potentials in the blood were measured at 2-week intervals. After 4 weeks, weight gain in the PT extract-fed group was significantly higher than that in the negative control group. However, food intake, food efficiency ratio, and weight index were not significantly different between the groups. The blood antioxidative potentials in the PT extract-fed group were higher than those in the negative control group. Free radical generation in the blood in the ascorbic acid-fed group was higher than that in the negative control group. These results suggest that supplementation with Populus tomentiglandulosa extract had beneficial effects on antioxidant potential.

Keywords
Antioxidant potential
free radical generation
Sprague-Dawley rats
Populus tomentiglandulosa
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Information
  • Publisher :Agriculture and Life Sciences Research Institute, Kangwon National University
  • Publisher(Ko) :None
  • Journal Title :Journal of Agricultural, Life and Environmental Sciences
  • Volume : 32
  • No :3
  • Pages :353-359
  • Received Date : 2020-07-16
  • Revised Date : 2020-09-08
  • Accepted Date : 2020-09-21
  • DOI :https://doi.org/10.22698/jales.20200029
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